Institutions that use animals for federally-funded laboratory research must appoint an Institutional Animal Care and Use Committee (IACUC) that reviews research protocols, conducts evaluations and inspects animal facilities biannually. The IACUC reports to the NIH Office of Laboratory Animal Welfare (OLAW) annually, and is issued an animal welfare assurance number authorizing the conduct of research that uses animals. The IACUC is required to report significant noncompliance with animal use protocols, as well as any actions taken to correct identified problems.
Investigators who include animals in their research protocols must successfully complete animal care and use training provided by the Collaborative Institutional Training Initiative (CITI) and must seek the approval of the IACUC before work can commence and at three-year intervals thereafter. To submit a protocol to the IACUC, log into IRBNet , complete the necessary forms, and upload your forms to IRBNet.org as a new study.
For your reference, the Governing Principles for Animal Care and Use contains additional information. You can also refer to our FAQs, or call the Office of Research and Technology Transfer (ORTT) at 870-680-8568.