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There was no gunman on campus.

Statement from Arkansas State University:

Numerous first responders from the University Police Department, Jonesboro Police Department, Craighead County Sheriff’s Office, Arkansas State Police and other law enforcement agencies worked swiftly and cooperatively this afternoon in response to what eventually turned out to be a false alarm on the campus.

Apparently students were filming a video project near the Union, and costumed actors were reported by other students to 911 as possible campus intruders. These students have been located and interviewed by University Police Officers. As a result, it has been confirmed that there was no gunman on campus.

The university immediately put a lockdown in place while the Union and surrounding areas were searched and cleared. The university’s text and email alert system was used to notify students about the situation.

Chancellor Tim Hudson, Vice Chancellor Rick Stripling, and other representatives of the university administration also responded to campus to assist in the crisis response. The university response plan worked perfectly as designed.

No injuries were reported, and normal campus operations have resumed.

The University Police Department will continue to closely monitor the campus this evening as a precautionary measure.

Chancellor Hudson expressed the university’s appreciation to all law enforcement personnel who responded so quickly to the perceived threat.

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Assistant Professor of Biology


Education

  • Ph.D. - Biochemistry and Molecular Biology, Tottori University, Japan
  • M.S. - Life Science and Biotechnology, Shimane University, Japan
  • M.S. - Genetics and Plant Breeding, Beijing Agricultural University, China
  • B.S. - Genetics and Plant Breeding, Beijing Agricultural University, China

Courses Taught

  • Biology of the Cell (Lecture & Lab for undergraduates)
  • Advanced Cell Biology  (Lecture for graduate students)
  • Environmental Microbiology (Lecture for undergraduate and graduate students)
  • Biological Science Laboratory  (Lab for undergraduates)
  • Human Anatomy and Physiology Laboratory I and II  (Labs for undergraduates)
  • Independent Study  (For Molecular Biosciences Ph.D. Students)

Research Interests

Research in Dr. Zhou’s group is at the interface of cell biology and cancer-focused biomedical science.  Our long-term research interests are to understand how the cell signaling system controls the actin cytoskeleton, cell motility, and cancer invasiveness.  Specifically, we study two proteins: the versatile actin-regulatory protein CAP1 and the central signaling kinase Akt.  We employ a wide range of techniques and approaches that encompass the fields of cell biology, molecular biology, biochemistry and cancer biology, in combination with mammalian cell systems and mouse models for our studies.

Current Research Projects:

  • Mechanisms of the Phosphor-regulation of CAP1.  Our laboratory has recently identified the very first regulatory mechanism for CAP1, through phosphorylation at Ser307/Ser309.  We are investigating further molecular and biochemical mechanisms underlying the phosphor-regulation of CAP1 in promoting actin dynamics.  Moreover, we are dissecting signaling pathways that control the actin cytoskeleton through the reversible phosphorylation of CAP1 at the tandem site.  De-regulated CAP1 has been implicated in the invasiveness of human cancers, and we are also investigating potential roles of the CAP1 regulation in human cancers.
  • Isoform-specific Roles for Akt1 and Akt2 in Pancreatic Cancer.  Our earlier work identified a mechanism for Akt to stimulate cell motility by linking to the Rac/PAK signaling.  Our follow-up study was also among the first to unravel isoform-specific roles for Akt in cell motility and cancer invasiveness.  These studies carry important translational potential because inhibitors for the frequently hyper-activated PI3-kinase/Akt signaling have been widely pursued for targeted cancer therapeutics.  Studies so far have revealed cancer-type dependent roles for Akt isoforms; however, little is known about roles for Akt isoforms in pancreatic cancer, for which targeting Akt has been proposed and attempted.


 


Guolei Zhou


Contact Information

P: 870-680-8588
F: 870-972-2638


Office

Building: ABI
Room: 209