Jianfeng (Jay) Xu
Professor
Office: 870 680 4812
Fax: 870 680 4348
Email: jxu@astate.edu
Biography
Research Associate and Lab Manager
Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY
Projects: Cell-free protein expression and site-specific protein glycosylation
Protein engineering of cellulase and antimicrobial peptide
Gold nanoparticle mediated gene/siRNA delivery
Research Associate
Edison Biotechnology Institute and Department of Chemistry and Biochemistry, Ohio University, Athens, OH
Mentor: Marcia Kieliszewski (Associate Professor)
Projects: Plant cell culture for the expression of therapeutic proteins
Molecular design and expression of biopolymers with plant cell cultures
Elucidation of the Hydroxyproline-O-glycosylation code in plant cell wall proteins
Molecular cloning of Gum arabic glycoprotein backbone gene
Research Associate
Department of Chemical Engineering, Ohio University, Athens, OH
Mentor: Murray Moo-Young (Visiting Professor from University of Waterloo)
Projects: Plant cell culture in bioreactor for the production of gum Arabic glycoprotein
Separation and structural characterizations of Gum Arabic glycoproteins
Aspergillus fermentation for the production of recombinant protein (interlukin-6, GFP)
Design and construction of a multifunctional bioreactor (100L)
Research Associate
National Key Laboratory of Biochemical Engineering, Chinese Academy of Sciences, Beijing, China
Mentor: Zhiguo Su (Professor)
Projects: Large-scale Taxus cell cultures for the Production of Paclitaxel (Taxol®)
Paclitaxel isolation/purification
Plant tissue culture for the production of peroxidase
Research Scientist
Beijing Kaizheng Biotech Developing Ltd., Beijing, China
Mentor: Zhiguo Su (Professor)
Project: Purification and chemical modification of hemoglobin (Blood substitute)
Research Assistant
Department of Biochemical Engineering, Dalian University of Technology, Dalian, China
Mentor: Pusun Feng (Professor)
Projects: Large scale plant cell cultures for the production of secondary metabolites
Self-flocculated yeast fermentation for the continuous production of alcohol project
Filamentous fungi fermentation for the production of therapeutic polysaccharides
Education
- Ph.D -1997 Biochemical Engineering, Dalian University of Technology, Dalian, China
Mentor: Pusun Feng
Thesis: Process regulation and control of large-scale culture of Rhodiola Sachalinensis cells for the production of salidroside
- B.S. -1991 Environmental Engineering
Dalian University of Technology, Dalian, China
Mentor: Quan Xie
Thesis: Determination of prior order and classification of pullants with fuzzy mixed method
Areas of Expertise
- Plant cell/tissue culture;
- Plant cell wall protein and glycosylation;
- Bioreactor design and operation;
- Recombinant protein expression and purification;
- Plant molecular biology; Cell free protein expression and protein glycosylation
Honors and Awards
- China National Postdoctoral Research Funding granted-10,000RMB, December, 1997
- Xiang Fanglong Fellowship, Dalian University of Technology, October, 1995
- An-Gang Fellowship, Dalian University of Technology, June, 1994
- Excellent Graduate Student of Dalian University of Technology, July, 1991
- Member of American Society of Plant Biologist (ASPB)
- Member of American Institute of Chemical Engineer (AIChE)
